A low-power low-noise cmos for amplifier neural recording applications
Top Cited Papers
- 5 June 2003
- journal article
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Journal of Solid-State Circuits
- Vol. 38 (6), 958-965
- https://doi.org/10.1109/jssc.2003.811979
Abstract
There is a need among scientists and clinicians for low-noise low-power biosignal amplifiers capable of amplifying signals in the millihertz-to-kilohertz range while rejecting large dc offsets generated at the electrode-tissue interface. The advent of fully implantable multielectrode arrays has created the need for fully integrated micropower amplifiers. We designed and tested a novel bioamplifier that uses a MOS-bipolar pseudoresistor element to amplify low-frequency signals down to the millihertz range while rejecting large dc offsets. We derive the theoretical noise-power tradeoff limit - the noise efficiency factor - for this amplifier and demonstrate that our VLSI implementation approaches this limit by selectively operating MOS transistors in either weak or strong inversion. The resulting amplifier, built in a standard 1.5-μm CMOS process, passes signals from 0.025Hz to 7.2 kHz with an input-referred noise of 2.2 μVrms and a power dissipation of 80 μW while consuming 0.16 mm 2 of chip area. Our design technique was also used to develop an electroencephalogram amplifier having a bandwidth of 30 Hz and a power dissipation of 0.9 μW while maintaining a similar noise-power tradeoff.Keywords
This publication has 21 references indexed in Scilit:
- A multi channel chopper modulated neural recording systemPublished by Institute of Electrical and Electronics Engineers (IEEE) ,2005
- Silicon neural recording arrays with on-chip electronics for in-vivo data acquisitionPublished by Institute of Electrical and Electronics Engineers (IEEE) ,2003
- A low-power, low-noise CMOS amplifier for neural recording applicationsPublished by Institute of Electrical and Electronics Engineers (IEEE) ,2003
- A new dc baseline stabilization scheme for neural recording microprobesPublished by Institute of Electrical and Electronics Engineers (IEEE) ,2003
- Adaptive photoreceptor with wide dynamic rangePublished by Institute of Electrical and Electronics Engineers (IEEE) ,2002
- A 100-channel system for real time detection and storage of extracellular spike waveformsJournal of Neuroscience Methods, 1999
- Description and demonstration of a CMOS amplifier-based-system with measurement and stimulation capability for bioelectrical signal transductionBiosensors and Bioelectronics, 1998
- A CMOS IC for portable EEG acquisition systemsIEEE Transactions on Instrumentation and Measurement, 1998
- Micropower high-performance SC building block for integrated low-level signal processingIEEE Journal of Solid-State Circuits, 1985
- MOS transistors operated in the lateral bipolar mode and their application in CMOS technologyIEEE Journal of Solid-State Circuits, 1983