Singapore Malay Eye Study: rationale and methodology of 6‐year follow‐up study (SiMES‐2)
- 2 February 2012
- journal article
- Published by Wiley in Clinical & Experimental Ophthalmology
- Vol. 40 (6), 557-568
- https://doi.org/10.1111/j.1442-9071.2012.02763.x
Abstract
Background: To describe the rationale and study design of a follow-up epidemiological eye study among Singaporean Malay adults. Design: Follow-up prospective population-based study. Participants: Participants of the Singapore Malay Eye Study (SiMES-1), which was conducted from August 2004 to June 2006. Methods: This is a follow-up study of the 3280 participants who participated in the SiMES-1 and are residing in Singapore. All participants of this follow-up study will undergo various standardized validated questionnaires on socio-demographics, quality of life and impact of visual impairment. Participants will undergo assessment of blood pressure, anthropometry, presenting and best corrected visual acuity, subjective refraction, ocular biometry, slit lamp and dilated eye examination, Goldmann tonometry, optic disc imaging, digital lens and retinal photography. Retinal tomography, retinal optical coherence topography and fundus autofluorescence will also be performed. Gonioscopy and visual fields examination will be performed on selected individuals. Main Outcome Measures: Incidence, risk factors and impact of visual impairment and major eye diseases. Results: A total of 3280 people who participated in the SiMES-1 will be contacted and invited to participate in this follow-up study. It is estimated that 12.8% of the participants will be deceased and there will be an 80% participation rate for the survivors of SiMES-1 (approximately 2288 participants). Conclusion: SiMES-2 will be one of the few follow-up epidemiological eye studies among Asians and will determine the cumulative 6-year incidence, progression, risk factors and impact of major eye diseases in Singaporean Malay adults.Keywords
This publication has 88 references indexed in Scilit:
- Longitudinal Changes in Visual Acuity and Health-related Quality of Life: The Los Angeles Latino Eye StudyOphthalmology, 2010
- The Rotterdam Study: 2010 objectives and design updateEuropean Journal of Epidemiology, 2009
- The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXIII: The Twenty-five-Year Incidence of Macular Edema in Persons with Type 1 DiabetesOphthalmology, 2009
- The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXII: The Twenty-Five-Year Progression of Retinopathy in Persons with Type 1 DiabetesOphthalmology, 2008
- Prevalence and Causes of Low Vision and Blindness in a Rural Chinese Adult Population: The Handan Eye StudyOphthalmology, 2008
- The Relationship of Dietary ω-3 Long-Chain Polyunsaturated Fatty Acid Intake With Incident Age-Related Macular DegenerationJAMA Ophthalmology, 2008
- Causes of blindness and visual impairment in Pakistan. The Pakistan national blindness and visual impairment surveyBritish Journal of Ophthalmology, 2007
- Prevalence and causes of visual impairment and blindness in Sistan-va-Baluchestan Province, Iran: Zahedan Eye StudyBritish Journal of Ophthalmology, 2006
- Physical activity and the 15-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye StudyBritish Journal of Ophthalmology, 2006
- Incidence of age-related cataract over a 10-year interval: the Beaver Dam Eye StudyOphthalmology, 2002