Fibrinolytic Activity in Men with Acute Myocardial Infarction before 60 Years of Age

Abstract

Fibrinolytic activity in plasma after venous occlusion was determined on two consecutive days 1–5 years after an acute myocardial infarction sustained before the age of 60 years in a group of 66 non‐diabetic men with normal serum cholesterol levels, and in an age‐ and sex‐matched reference group of 32 men. The infarction group was divided into 2 subgroups: one with normal (n = 42), the other with elevated (n = 24) diastolic blood pressure. Variance analysis did not reveal any statistically significant differences in fibrinolytic activity after repeated provocation between the three groups, but in a Student's test the value was significantly lower in the infarction group with high diastolic pressure than in the reference group. A relationship was found between apolipoprotein AI and fibrinolytic activity after repeated provocation.