An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies
- 15 July 2010
- journal article
- Published by Elsevier BV in Journal of Neuroscience Methods
- Vol. 190 (2), 171-179
- https://doi.org/10.1016/j.jneumeth.2010.05.001
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- Alzheimer's disease: synaptic dysfunction and AβMolecular Neurodegeneration, 2009
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memoryNature Medicine, 2008
- Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomersMolecular Neurodegeneration, 2007
- Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and DistinctOnline Journal of Public Health Informatics, 2007
- High-resolution Atomic Force Microscopy of Soluble Aβ42 OligomersJournal of Molecular Biology, 2006
- Natural oligomers of the amyloid-β protein specifically disrupt cognitive functionNature Neuroscience, 2004
- Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of PathogenesisScience, 2003
- Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's DiseaseThe American Journal of Pathology, 1999
- Amyloid β-Protein FibrillogenesisJournal of Biological Chemistry, 1997
- NMR studies of amyloid .beta.-peptides: proton assignments, secondary structure, and mechanism of an .alpha.-helix .fwdarw. .beta.-sheet conversion for a homologous, 28-residue, N-terminal fragmentBiochemistry, 1992