Benzimidazole: An emerging scaffold for analgesic and anti-inflammatory agents
Top Cited Papers
- 1 April 2014
- journal article
- review article
- Published by Elsevier BV in European Journal of Medicinal Chemistry
- Vol. 76, 494-505
- https://doi.org/10.1016/j.ejmech.2014.01.030
Abstract
No abstract availableKeywords
This publication has 60 references indexed in Scilit:
- Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP)Bioorganic & Medicinal Chemistry, 2012
- 5-Lipoxygenase-activating protein inhibitors. Part 3: 3-{3-tert-Butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl]-5-(5-methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM643)—A potent FLAP inhibitor suitable for topical administrationBioorganic & Medicinal Chemistry Letters, 2010
- Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular RisksPharmaceuticals, 2010
- Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agentsEuropean Journal of Medicinal Chemistry, 2010
- Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivativesBioorganic & Medicinal Chemistry Letters, 2010
- The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)Bioorganic & Medicinal Chemistry Letters, 2006
- Inhibition of Tpl2 kinase and TNFα production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritisBioorganic & Medicinal Chemistry Letters, 2006
- Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazolesJournal of Medicinal Chemistry, 2006
- Prostaglandin synthase 2Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996
- Synthesis and Antiinflammatory and Analgesic Properties of 2-Amino-1H-benzimidazole and 1,2-Dihydro-2-iminocycloheptimidazole Derivatives.CHEMICAL & PHARMACEUTICAL BULLETIN, 1993