Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors
- 13 January 2007
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry Letters
- Vol. 17 (6), 1634-1640
- https://doi.org/10.1016/j.bmcl.2006.12.114
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Carba Analogs of Cyclic Phosphatidic Acid Are Selective Inhibitors of Autotaxin and Cancer Cell Invasion and MetastasisPublished by Elsevier BV ,2006
- Phosphorothioate Analogues of Alkyl Lysophosphatidic Acid as LPA3 Receptor‐Selective AgonistsChemMedChem, 2006
- Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptorsBioorganic & Medicinal Chemistry Letters, 2006
- Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligandsBioorganic & Medicinal Chemistry Letters, 2005
- A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonistBioorganic & Medicinal Chemistry Letters, 2004
- Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acidBioorganic & Medicinal Chemistry Letters, 2004
- Lysophosphatidic acid production and action: Validated targets in cancer?Journal of Cellular Biochemistry, 2004
- Identifying Specific Conformations by Using a Carbohydrate Scaffold: Discovery of Subtype‐Selective LPA‐Receptor Agonists and an AntagonistAngewandte Chemie-International Edition, 2004
- The emerging role of lysophosphatidic acid in cancerNature Reviews Cancer, 2003
- Structure activity relationships of lysophospholipid mediatorsProstaglandins & Other Lipid Mediators, 2001