High seroprevalence of Epstein–Barr virus in children with multiple sclerosis
- 12 December 2006
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 67 (11), 2063-2065
- https://doi.org/10.1212/01.wnl.0000247665.94088.8d
Abstract
We studied seroprevalence and concentrations of Epstein–Barr virus (EBV) antibodies in 147 pediatric patients with multiple sclerosis (MS) and paired controls. The children with MS showed a near-complete seropositivity for EBV antibody against virus capsid antigen (98.6% vs 72.1% in controls, p = 0.001) but did not display serologic evidence for a recent EBV infection. EBV antibody concentrations of pediatric patients with MS were significantly higher vs controls.Keywords
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