Lactic Acidosis Associated with Hodgkin's Disease

Abstract

LACTIC ACIDOSIS has been recognized as a cause of metabolic acidosis in patients with neoplastic disorders without clinically evident tissue hypoxia; it is associated with a poor prognosis in such patients.¹⁷ Treatment has included alkalizing therapy with bicarbonate or tromethamine (THAM) and the use of methylene blue or dialysis, but the results have frequently been disappointing.⁸ This report describes a patient with severe lactic acidosis that developed during the relapse of Hodgkin's disease and was rapidly resolved as a result of remission of the Hodgkin's disease with chemotherapy.Case ReportA 30-year-old man was admitted to Brookdale Hospital Medical Center . . .