Comparison of radiographic joint space width with magnetic resonance imaging cartilage morphometry: Analysis of longitudinal data from the osteoarthritis initiative
Open Access
- 29 June 2010
- journal article
- research article
- Published by Wiley in Arthritis Care & Research
- Vol. 62 (7), 932-937
- https://doi.org/10.1002/acr.20148
Abstract
Objective Magnetic resonance imaging (MRI) and radiography are established imaging modalities for the assessment of knee osteoarthritis (OA). The objective of our study was to compare the responsiveness of radiographic joint space width (JSW) with MRI‐derived measures of cartilage morphometry for OA progression in participants from the Osteoarthritis Initiative (OAI). Methods This study examined the baseline and 12‐month visits of a subset of 150 subjects from the OAI. Measurement of radiographic JSW was facilitated by the use of automated software that delineated the femoral and tibial margins of the joint. Measures of medial compartment minimum JSW and JSW at fixed locations were compared with cartilage morphometry measures derived from MRI. The results were stratified by Kellgren/Lawrence (K/L) scale grade and by tibiofemoral anatomic axis angle. In order to examine the relative responsiveness of various techniques, we calculated the standardized response mean (SRM) between the 2 visits. Results The SRM for radiographic JSW measured at the optimal location was −0.32 compared with −0.39 for the most responsive MRI measure. For the subgroup with a K/L scale grade of 2 or 3, the most responsive SRM values were −0.34 for radiographic JSW and −0.42 for MRI. Conclusion Our study demonstrates that new measures using a software analysis of digital knee radiographic images are comparable with MRI in detecting OA progression, and potentially superior when considering the cost‐effectiveness of the 2 imaging modalities.Keywords
This publication has 23 references indexed in Scilit:
- Location specific radiographic joint space width for osteoarthritis progressionOsteoarthritis and Cartilage, 2009
- Change in cartilage morphometry: a sample of the progression cohort of the Osteoarthritis InitiativeAnnals Of The Rheumatic Diseases, 2008
- Knee osteoarthritis. Efficacy of a new method of contrast-enhanced musculoskeletal ultrasonography in detection of synovitis in patients with knee osteoarthritis in comparison with magnetic resonance imagingAnnals Of The Rheumatic Diseases, 2008
- Double echo steady state magnetic resonance imaging of knee articular cartilage at 3 Tesla: a pilot study for the Osteoarthritis InitiativeAnnals Of The Rheumatic Diseases, 2006
- A comparative assessment of alignment angle of the knee by radiographic and physical examination methodsArthritis & Rheumatism, 2005
- Measurement of radiographic joint space width in the tibiofemoral compartment of the osteoarthritic knee: Comparison of standing anteroposterior and Lyon Schuss viewsArthritis & Rheumatism, 2003
- Reexamining the Sarcopenia Hypothesis: Muscle Mass versus Muscle StrengthAnnals of the New York Academy of Sciences, 2000
- Precision of joint space width measurement in knee osteoarthritis from digital image analysis of high definition macroradiographsOsteoarthritis and Cartilage, 1993
- Development of a new radiographic scoring system using digital image analysis.Annals Of The Rheumatic Diseases, 1989
- Radiological Assessment of Osteo-ArthrosisAnnals Of The Rheumatic Diseases, 1957