Paracetamol-induced fixed drug eruption with positive immunofluorescence findings
- 1 July 1990
- journal article
- Published by Oxford University Press (OUP) in Clinical and Experimental Dermatology
- Vol. 15 (4), 293-295
- https://doi.org/10.1111/j.1365-2230.1990.tb02093.x
Abstract
A 93-year-old woman with an 8-year history of episodes of fixed drug eruption due to paracetamol is described. The rash was characterized by bullae, crusted lesions, hyperpigmented and erythematous patches as well as lesions resembling toxic epidermal necrolysis. Direct immunofluorescence revealed deposition of IgG and C3 in the epidermal intercellular cement substance of lesional skin only; the pathogenetic significance of this finding is discussed.Keywords
This publication has 8 references indexed in Scilit:
- Wandering fixed drug eruption: A mucocutaneous reaction to acetaminophenJournal of the American Academy of Dermatology, 1987
- Fixed drug eruption: an immunohistochemical investigation of the acute and healing phaseBritish Journal of Dermatology, 1987
- Fixed drug eruption due to paracetamolBritish Journal of Dermatology, 1986
- Fixed drug eruption. A brief reviewArchives of Dermatology, 1984
- A fixed drug eruption due to paracetamolBritish Journal of Dermatology, 1975
- Fixed drug eruption (phenolphthalein). Evidence for a blood-borne mediatorArchives of Dermatology, 1972
- DEMONSTRATION OF INTERCELLULAR IMMUNOFLUORESCENCE AND EPIDERMAL HYSTERESIS IN BULLOUS FIXED DRUG ERUPTION DUE TO PHENOLPHTHALEINBritish Journal of Dermatology, 1972
- Dermatitis Medicamentosa Due to AntipyrineA.M.A. Archives of Dermatology, 1957