Percutaneous Nephrolithotripsy in Patients with Diabetes Mellitus
- 1 January 2009
- journal article
- clinical trial
- Published by Mary Ann Liebert Inc in Journal of Endourology
- Vol. 23 (1), 21-26
- https://doi.org/10.1089/end.2008.0282
Abstract
To compare the surgical outcomes in a cohort of patients with diabetes who were undergoing percutaneous nephrolithotripsy (PCNL) for renal stone disease to a nondiabetic group of patients at a single center. Between July 1990 and December 2005, all patients scheduled for PCNL were prospectively included in a single-center database. Preoperative, intraoperative, and postoperative data were prospectively collected and analyzed. Primary outcomes evaluated were stone-free rates and complications, including the need for blood transfusion, while the secondary outcome was length of hospital stay. This report specifically reviews these outcomes in patients known to have diabetes at the time of surgery. Both outcomes were compared with those obtained in our nondiabetic patient population. Analysis of the data from 183 (13.7%) patients with diabetes of the 1338 patients undergoing PCNL revealed that patient age (63.1 years), surgical time (90.8 minutes), and complications (major 2.2%), including need for transfusion (0.5%) and stone-free rate (94.5%), were not significantly different from those observed in our nondiabetic patients. The average length of hospital stay was significantly longer in the diabetic group (4.4 days vs 3.9 days, P = 0.022). Uric acid stone composition was found to be the most common stone composition among the patients with diabetes in this study (41%). PCNL can be performed with excellent stone-free rates and with an acceptable complication risk in the diabetic population. The incidence of uric acid stone disease appears to be significantly higher than previously reported and warrants heightened efforts directed toward stone prevention in this population.Keywords
This publication has 25 references indexed in Scilit:
- Urine Composition in Type 2 DiabetesJournal of the American Society of Nephrology, 2006
- Diabetes mellitus and the risk of nephrolithiasisKidney International, 2005
- High prevalence of uric acid calculi in diabetic stone formersNephrology Dialysis Transplantation, 2005
- Urinary Stone Disease in Diabetes MellitusScandinavian Journal of Urology and Nephrology, 2003
- IS THERE A ROLE FOR OPEN STONE SURGERY?Urologic Clinics of North America, 2000
- The Changing Practice of Percutaneous Stone Surgery. Review of 1000 Cases 1981–1988British Journal of Urology, 1990
- Percutaneous Renal and Ureteric Stone ExtractionScandinavian Journal of Urology and Nephrology, 1989
- Percutaneous nephrolithotomy: Analysis of 500 consecutive casesUrologic Radiology, 1986
- Percutaneous Nephrolithotomy: A Report of 150 CasesBritish Journal of Urology, 1985
- Percutaneous Removal of Kidney Stones: Review of 1,000 CasesJournal of Urology, 1985