BLOOD TRANSFUSION: A POSSIBLE RISK FACTOR IN RETROLENTAL FIBROPLASIA
- 1 July 1981
- journal article
- Published by Wiley in Acta Paediatrica
- Vol. 70 (4), 535-539
- https://doi.org/10.1111/j.1651-2227.1981.tb05736.x
Abstract
The effect of blood transfusion on the occurrence of RLF was evaluated in 58 infants who weighed less than 1001 g at birth (Group I) and 70 oxygen treated infants of various birth weights (Group II). Although there was no significant difference between Group I infants with or without exchange transfusion as to birth weight, gestational age, duration of oxygen therapy, peak Pa02's, or multiple births, there was a significantly increased incidence of pre-retrolental fibroplasia in transfused over non-transfused Group II infants. When Group II infants were stratified for prematurity and oxygen duration, this difference persisted in those not already at risk for RLF. This increased incidence of retinopathy in transfused infants suggests that blood transfusion may be a risk factor in the pathogenesis of RLF.Keywords
This publication has 11 references indexed in Scilit:
- INCIDENCE OF RETROLENTAL FIBROPLASIAThe Lancet, 1978
- PHOTOSENSITIZED SHIFT IN THE O2DISSOCIATION CURVE OF FETAL BLOODActa Paediatrica, 1974
- RETROLENTAL FIBROPLASIA IN SWEDEN General Survey and Selected Study on Patients born in 1960–1966Acta Paediatrica, 1973
- Proliferative Retinopathy in Anencephalic BabiesAmerican Journal of Ophthalmology, 1972
- Exchange transfusion in the newborn infant with fresh and “old” blood: The role of storage on 2,3-diphosphoglycerate, hemoglobin-oxygen affinity, and oxygen releaseThe Journal of Pediatrics, 1971
- Retrolental Fibroplasia--Associated With Intrauterine Anoxia?American Journal of Ophthalmology, 1968
- Recent increase in mortality from byaline membrane diseaseThe Journal of Pediatrics, 1960
- Retrolental FibroplasiaA.M.A. Archives of Ophthalmology, 1956
- Role of Oxygen in the Genesis of Retrolental Fibroplasia: A Preliminary ReportBritish Journal of Ophthalmology, 1953
- Extreme Prematurity and Fibroblastic Overgrowth of Persistent Vascular Sheath Behind Each Crystalline Lens* *From the Massachusetts Eye and Ear Infirmary. This investigation is made possible through the Special Fund for Research for Pathology Laboratory.American Journal of Ophthalmology, 1942