Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes
Open Access
- 7 December 2011
- journal article
- research article
- Published by Hindawi Limited in Journal of Obesity
- Vol. 2011, 1-5
- https://doi.org/10.1155/2011/350523
Abstract
Background. We investigated the effect of laparoscopic sleeve gastrectomy (LSG) on morbidly obese diabetics and examined the short-term impact of LSG on diabetic medication cost.Methods. A prospective database of consecutive bariatric patients was reviewed. Morbidly obese patients with type 2 diabetes who underwent LSG were included in the study. Age, gender, body mass index (BMI), diabetic medication use, glucose, insulin, and HbA1c levels were documented preoperatively, and at 2 weeks, 2 months, 6 months, and 12 months postoperatively. Insulin resistance was estimated using the homeostatic model assessment (HOMA). Use and cost of diabetic medications were followed.Results. Of 178 patients, 22 were diabetics who underwent LSG. Diabetes remission was observed in 62% of patients within 2 months and in 75% of patients within 12 months. HOMA-IR improved after only two weeks following surgery (16.5 versus 6.6, ). Average number of diabetic medications decreased from 2.2 to Conclusion. Morbidly obese patients with diabetes who undergo LSG have high rates of diabetes remission early after surgery. This translates to a significant medication cost savings.Keywords
This publication has 30 references indexed in Scilit:
- Bariatric Surgery Significantly Decreases the Prevalence of Type 2 Diabetes Mellitus and Pre-Diabetes among Morbidly Obese Multiethnic Adults: Long-Term ResultsJournal of the American College of Surgeons, 2011
- Sleeve gastrectomy and type 2 diabetes mellitus: a systematic reviewSurgery for Obesity and Related Diseases, 2010
- Early Postoperative Outcomes of Metabolic Surgery to Treat Diabetes From Sites Participating in the ASMBS Bariatric Surgery Center of Excellence Program as Reported in the Bariatric Outcomes Longitudinal DatabaseAnnals of Surgery, 2010
- Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetesSurgical Endoscopy, 2009
- Results of laparoscopic sleeve gastrectomy: A prospective study in 135 patients with morbid obesitySurgery, 2009
- Weight Loss, Appetite Suppression, and Changes in Fasting and Postprandial Ghrelin and Peptide-YY Levels After Roux-en-Y Gastric Bypass and Sleeve GastrectomyAnnals of Surgery, 2008
- Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesitySurgical Endoscopy, 2006
- Bariatric Surgery is a Cost-saving for the Healthcare SystemObesity Surgery, 2005
- The Early Effect of the Roux-en-Y Gastric Bypass on Hormones Involved in Body Weight Regulation and Glucose MetabolismAnnals of Surgery, 2004
- Who Would Have Thought It? An Operation Proves to Be the Most Effective Therapy for Adult-Onset Diabetes MellitusAnnals of Surgery, 1995