A Novel Staphylococcal Cassette Chromosomal Element, SCC fusC , Carrying fusC and speG in Fusidic Acid-Resistant Methicillin-Resistant Staphylococcus aureus

Abstract
A high prevalence of fusC (16/46, 59%) was found in fusidic acid-resistant methicillin-resistant Staphylococcus aureus isolates collected from 2008 to 2010. Nucleotide sequencing of fusC and flanking regions revealed a novel staphylococcal cassette chromosome (SCC) structure, SCC fusC , which was integrated into rlmH and located upstream from SCC mec . The SCC fusC element contained speG , which may contribute to the polyamine resistance.

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