Multisite Investigation of Traumatic Brain Injuries, Posttraumatic Stress Disorder, and Self-reported Health and Cognitive Impairments

Abstract
Traumatic brain injury (TBI) constitutes a major public health problem for both veteran and civilian trauma-exposed patient populations.1-7 The US involvement in the current Iraq and Afghanistan conflicts has brought the interrelationship between TBI and posttraumatic stress disorder (PTSD) to the forefront of medical research, commentary, and practice.8-19 Many earlier studies of TBI and PTSD focused on injured civilians presenting with a full spectrum of mild, moderate, and severe TBI.20-33 More recent published investigations have focused on returning soldiers with mild TBI1,34,35 and the substantial number of wounded combat veterans who incur varying degrees of TBI in conjunction with multiple injuries to other body regions.36-40

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