Molecular cloning and expression of cDNAs for the human interleukin-2 receptor
- 1 October 1984
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 311 (5987), 626-631
- https://doi.org/10.1038/311626a0
Abstract
The human T-cell growth factor (interleukin-2) receptor was purified. cDNA [complementary DNA] corresponding to this receptor were cloned sequenced and expressed. One gene, but 2 interleukin-2 receptor mRNA which differ in their polyadenylation signals were identified. An additional cDNA that may correspond to an alternatively spliced mRNA that lacks a 216 base segment and appears to encode an altered membrane protein which cannot bind interleukin-2 was isolated.This publication has 38 references indexed in Scilit:
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