GeneExpressionSignature: an R package for discovering functional connections using gene expression signatures
- 1 February 2013
- journal article
- research article
- Published by Mary Ann Liebert Inc in OMICS: A Journal of Integrative Biology
- Vol. 17 (2), 116-118
- https://doi.org/10.1089/omi.2012.0087
Abstract
Comparisons of gene expression signatures provide a way to explore functional connections among biological events in global aspects of cell response. GeneExpressionSignature is an R package developed for the large-scale analysis of gene expression signatures. The package implements two rank-merging algorithms and two similarity-scoring algorithms. The functions of GeneExpressionSignature provide a flexible solution for gene expression signature-based studies and hold great potential in biomedical research applications, such as drug repurposing. GeneExpressionSignature is released under GPL v2 within the Bioconductor project and is freely available at http://www.bioconductor.org/packages/release/bioc/html/GeneExpressionSignature.html.Keywords
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