Prospective Clinical Assessments of Hospitalized Patients With Positive SARS-CoV-2 PCR Tests for Necessity of Isolation

Abstract

We prospectively assessed 536 hospitalized patients with positive SARS-CoV-2 PCR tests for infectiousness based on symptoms, cycle thresholds, and SARS-CoV-2 history, with repeat testing and serologies in select cases. 148 (28%) patients were deemed non-infectious, most with evidence of prior infection, and managed on standard precautions without evidence of transmission.