Nanoparticle‐based pseudostationary phases in capillary electrochromatography
- 18 January 2006
- journal article
- review article
- Published by Wiley in Electrophoresis
- Vol. 27 (1), 76-83
- https://doi.org/10.1002/elps.200500535
Abstract
During the past decades, research has been performed to enhance selectivity in CE by introducing different types of additives into the electrolyte. Research concerning this has taken many directions, especially during the last 5 years. A promising technique, which benefits from no packing or frits, is to use nanoparticles as the pseudostationary phase (PSP) in CEC. PSPs have the advantage of introducing a novel interaction phase for every analysis, which greatly simplify column exchange and circumvent contamination inherited from complex mixtures, e.g., biological samples. The field of nanoparticle‐based PSPs used in CEC is covered in this review. The term CEC will be used consequently throughout this review, although some authors used the term EKC to categorize their work. Important requirements for the nanoparticles used and possible reasons for band broadening will be discussed. Applications with silica nanoparticles, polymer nanoparticles, molecularly imprinted polymer nanoparticles, gold nanoparticles, dendrimers, and polymeric surfactants as PSP will also be discussed.Keywords
This publication has 47 references indexed in Scilit:
- Nanoparticle‐filled capillary electrophoresis for the separation of long DNA molecules in the presence of hydrodynamic and electrokinetic forcesElectrophoresis, 2005
- On-line capillary electrophoresis-mass spectrometry using dopant-assisted atmospheric pressure photoionization: Setup and system performanceElectrophoresis, 2004
- Use of polystyrene nanoparticles to enhance enantiomeric separation of propranolol by capillary electrophoresis with Hp-beta-CD as chiral selectorAnalytica Chimica Acta, 2004
- Polymeric alkenoxy amino acid surfactants: II. Chiral separations of β‐blockers with multiple stereogenic centersElectrophoresis, 2004
- Polymeric sulfated surfactants with varied hydrocarbon tail: I. Synthesis, characterization, and application in micellar electrokinetic chromatographyElectrophoresis, 2004
- Phosphate buffers in capillary electrophoresis/mass spectrometry using atmospheric pressure photoionization and electrospray ionizationRapid Communications in Mass Spectrometry, 2003
- Polymeric alkenoxy amino acid surfactants: I. Highly selective class of molecular micelles for chiral separation of β‐blockersElectrophoresis, 2003
- Manipulation of separation selectivity for alkali metals and ammonium in ion-exchange capillary electrochromatography using a suspension of cation exchange particles in the electrolyte as a pseudostationary phaseElectrophoresis, 1999
- Novel pseudostationary phase for micellar electrokinetic capillary chromatographyJournal of Microcolumn Separations, 1992
- Starburst Dendrimers as Carriers in Electrokinetic ChromatographyChemistry Letters, 1992