Sodium Valproate in the Treatment of Intractable Childhood Epilepsy
- 1 April 1975
- journal article
- Published by Wiley in Developmental Medicine and Child Neurology
- Vol. 17 (2), 175-181
- https://doi.org/10.1111/j.1469-8749.1975.tb03469.x
Abstract
Sodium valproate has been used, in combination with a variety of standard anticonvulsant drugs, to treat 24 children with intractable epilepsy. A reduction of fit frequency greater than 90 percent was obtained in six patients, and a reduction of over 50 per cent in another six, with an improvement in alertness and school performance in the majority of cases. Grand mal, myoclonic and petit mal epilepsy gave the best response, while infantile spasms responded least well. No serious side-effects were encountered.This publication has 5 references indexed in Scilit:
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