Asplenia in two father‐son Pairs
- 13 March 1995
- journal article
- case report
- Published by Wiley in American Journal of Medical Genetics
- Vol. 56 (1), 10-11
- https://doi.org/10.1002/ajmg.1320560104
Abstract
We report on two father‐son pairs with isolated nonsyndromal asplenia. This may represent autosomal dominant inheritance of a mutation in a gene involved with spleen development and determination of laterality. The incidence of hereditary isolated asplenia is unknown; therefore, screening for asplenia in first degree relatives of individuals with (poly)asplenia should be considered.Keywords
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