Aerobic Visible-Light Photoredox Radical C–H Functionalization: Catalytic Synthesis of 2-Substituted Benzothiazoles
- 6 December 2011
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 14 (1), 98-101
- https://doi.org/10.1021/ol2028866
Abstract
An aerobic visible-light driven photoredox catalytic formation of 2-substituted benzothiazoles through radical cyclization of thioanilides has been accomplished. The reaction features C–H functionalization and C–S bond formation with no direct metal involvement except the sensitizer. The reaction highlights the following: (1) visible-light is the reaction driving force; (2) molecular oxygen is the terminal oxidant, and (3) water is the only byproduct.Keywords
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