Risk factors for primary open-angle glaucoma in Japanese subjects attending community health screenings
Open Access
- 1 October 2011
- journal article
- research article
- Published by Taylor & Francis Ltd in Clinical Ophthalmology
- Vol. 5, 1531-1537
- https://doi.org/10.2147/opth.s26049
Abstract
Background/aims: To describe risk factors associated with primary open-angle glaucoma (POAG) in Japanese subjects who participated in community health screenings. Methods: Residents of Akita, Japan, participating in a community health checkup were selected to undergo a comprehensive ophthalmic examination. Glaucoma was diagnosed based on optic disk appearance, perimetric results, and other ocular findings. Systemic blood pressure and intraocular pressure were measured and ocular perfusion pressure was calculated. Logistic regression analysis was performed to determine risk factors for POAG patients. Results and conclusion: Of the 710 subjects examined, 26 had POAG. The estimated prevalence of POAG was 3.7%. After adjusting for age, the prevalence of POAG was similar to that found in the Tajimi Study of Japanese subjects. Multivariate logistic regression analysis demonstrated that older age (≥60 years, odds ratio [OR]: 3.49), lower diastolic blood pressure (≤58 mmHg, OR: 2.11), higher intraocular pressure (≥19 mmHg, OR: 4.12), and lower ocular perfusion pressure (≤34 mmHg, OR: 5.78) were associated with increased risk of having POAG. These findings may be relevant for identifying high risk groups.Keywords
This publication has 31 references indexed in Scilit:
- Primary Open-Angle GlaucomaThe New England Journal of Medicine, 2009
- Screening for Open Angle Glaucoma: Systematic Review of Cost-effectiveness StudiesJournal of Glaucoma, 2008
- Systemic Antihypertensive Medication and Incident Open-angle GlaucomaOphthalmology, 2007
- Association of Blood Pressure Status With the Optic Disk Structure in Non-glaucoma Subjects: The Thessaloniki Eye StudyAmerican Journal of Ophthalmology, 2006
- A Sick Eye in a Sick Body? Systemic Findings in Patients with Primary Open-angle GlaucomaSurvey of Ophthalmology, 2006
- The Tajimi Study Report 2: Prevalence of Primary Angle Closure and Secondary Glaucoma in a Japanese PopulationOphthalmology, 2005
- The Role of Optic Nerve Blood Flow in the Pathogenesis of GlaucomaOphthalmology Clinics of North America, 2005
- Possible association between heavy computer users and glaucomatous visual field abnormalities: a cross sectional study in Japanese workersJournal of Epidemiology and Community Health, 2004
- Association between Nocturnal Blood Pressure Reduction and Progression of Visual Field Defect in Patients with Primary Open-Angle Glaucoma or Normal-Tension GlaucomaJapanese Journal of Ophthalmology, 2004
- Genetic Risk of Primary Open-angle GlaucomaAmerican Journal of Ophthalmology, 1998