Predictors of Good Outcome After Stent-Retriever Thrombectomy in Acute Basilar Artery Occlusion
- 1 October 2015
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Stroke
- Vol. 46 (10), 2972-2975
- https://doi.org/10.1161/strokeaha.115.010840
Abstract
Background and Purpose—: Factors related to prognosis after a modern mechanical thrombectomy in patients with acute basilar artery occlusion remain unclear. This study investigated the prognostic factors for patients with acute basilar artery occlusion who underwent a stent-retriever thrombectomy. Methods—: We analyzed clinical and pretreatment diffusion-weighted imaging (DWI) data in 50 consecutive patients with acute basilar artery occlusion treated with stent-retriever thrombectomy. A good outcome was defined as a modified Rankin Scale score of 0 to 2 at 3 months. The association between clinical and DWI parameters and functional outcome was evaluated with logistic regression analysis. Results—: In a univariate analysis, the following variables were significantly associated with outcome: age, hypertension, baseline National Institutes of Health Stroke Scale, posterior circulation Acute Stroke Prognosis Early CT Score on a pretreatment DWI, posterior circulation Acute Stroke Prognosis Early CT Score of ≥7 (versus P =0.008) and high DWI posterior circulation Acute Stroke Prognosis Early CT Score (odds ratio, 1.854; 95% confidence interval 1.012–3.397; P =0.045) were significant independent predictors of good outcome. In a univariate analysis, bilateral thalamic infarction was associated with a poor outcome (odds ratio, 1.993; 95% confidence interval, 1.187–3.346; P =0.035) but not with a unilateral thalamic infarction ( P =0.525). Conclusions—: This study suggested that initial infarction severity and posterior circulation Acute Stroke Prognosis Early CT Score on a pretreatment DWI are independent predictors of clinical outcome after stent-retriever thrombectomy in patients with acute basilar artery occlusion.Keywords
This publication has 15 references indexed in Scilit:
- Acute Basilar Artery Occlusion: Outcome of Mechanical Thrombectomy with Solitaire Stent within 8 Hours of Stroke OnsetAmerican Journal of Neuroradiology, 2013
- Thrombolysis of basilar artery occlusion: Impact of baseline ischemia and timeAnnals of Neurology, 2013
- Time is Brain(stem) in Basilar Artery OcclusionStroke, 2012
- MRI in Patients with Acute Basilar Artery Occlusion – DWI Lesion Scoring is an Independent Predictor of OutcomeInternational Journal of Stroke, 2011
- Extent of Hypoattenuation on CT Angiography Source Images in Basilar Artery OcclusionStroke, 2011
- Diffusion-Weighted MRI Helps Predict Outcome in Basilar Artery Occlusion Patients Treated with Intra-Arterial ThrombolysisCerebrovascular Diseases, 2011
- Three-Month and Long-Term Outcomes and Their Predictors in Acute Basilar Artery Occlusion Treated With Intra-Arterial ThrombolysisStroke, 2011
- Topographic patterns of thalamic infarcts in association with stroke syndromes and aetiologiesJournal of Neurology, Neurosurgery & Psychiatry, 2011
- Evolution of Neurological, Neuropsychological and Sleep-Wake Disturbances After Paramedian Thalamic StrokeStroke, 2008
- Basilar artery occlusion: clinical and radiological correlation.Stroke, 1977