Cardiovascular Disease After Aromatase Inhibitor Use

Abstract
Aromatase inhibitors (AIs) are considered superior to tamoxifen citrate in reducing recurrence risk in postmenopausal women with hormone receptor–positive breast cancer.1,2 However, although tamoxifen has favorable effects on lipid profiles, AIs have unfavorable effects, raising questions on whether these 2 therapies differentially affect cardiovascular disease (CVD) risk.3-9