Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family
Open Access
- 22 December 2009
- journal article
- research article
- Published by Springer Science and Business Media LLC in BMC Cell Biology
- Vol. 10 (1), 95
- https://doi.org/10.1186/1471-2121-10-95
Abstract
Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge. Tight junctions are formed by multiprotein complexes containing cytosolic and transmembrane proteins. How these components work together to form functional tight junctions is still not well understood and will require a complete understanding of the molecular composition of the junction.Keywords
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