Linear relationship of refractive and biometric lenticular changes during accommodation in emmetropic and myopic eyes
- 18 October 2006
- journal article
- Published by BMJ in British Journal of Ophthalmology
- Vol. 91 (3), 360-365
- https://doi.org/10.1136/bjo.2006.099879
Abstract
Aim: Aim of this study was to investigate the relationship between refractive changes in the eye and biometric changes of the human crystalline lens during accommodation. Furthermore, differences in these relationships between young, healthy emmetropic and myopic subjects were analyzed. Methods: Mean relative change in anterior chamber depth (ACD), lens thickness (LT), anterior segment length (ASL = ACD + LT) and in objective refraction were simultaneously assessed during near-point-induced accommodation in 10 emmetropic and 10 myopic subjects. Via a beam splitter, measurements were performed simultaneously using partial coherence interferometry (PCI) and infrared (IR) photorefraction. Results: On average, for each diopter of accommodation LT increased by 0.063 mm in emmetropic and by 0.072 mm in myopic eyes, and ACD decreased by 0.047 mm and 0.057 mm, respectively. Mean ASL, indicating the position of the posterior lens pole, increased by 0.009 mm in emmetropic and by 0.013 mm in myopic eyes. The correlation between refractive and biometric changes was found to be essentially linear in both subgroups. Differences in ACD between emmetropic and myopic eyes were statistically significant at an accommodative stimulus of –1 D (p<0.04) and –2 D (p<0.02). Conclusion: The biometric and refractive changes of the human lens are highly correlated and linear in function in both emmetropic and myopic eyes.Keywords
This publication has 36 references indexed in Scilit:
- The mechanism of presbyopiaProgress in Retinal and Eye Research, 2005
- Accuracy of a new photorefractometer in young and adult patientsAlbrecht von Graefes Archiv für Ophthalmologie, 2005
- Subjective and objective measurement of human accommodative amplitudeJournal of Cataract & Refractive Surgery, 2003
- The mechanism of accommodation in primates11The authors have no commercial interests or conflict of interests with anything presented in this study.Ophthalmology, 1999
- Biometric, optical and physical changes in the isolated human crystalline lens with age in relation to presbyopiaVision Research, 1999
- Partial coherence interferometry: a novel approach to biometry in cataract surgeryAmerican Journal of Ophthalmology, 1998
- Accommodation and presbyopia in the human eye. Changes in the anterior segment and crystalline lens with focus.1997
- Microfluctuations of steady‐state accommodation measured with ultrasonographyOphthalmic and Physiological Optics, 1996
- Analysis of accommodation function with ultrasonographyDocumenta Ophthalmologica, 1996
- Inter‐individual variability in the dynamics of natural accommodation in humans: relation to age and refractive errors.The Journal of Physiology, 1993