High 18F-FDG Uptake in Synthetic Aortic Vascular Grafts on PET/CT in Symptomatic and Asymptomatic Patients
Open Access
- 15 September 2008
- journal article
- Published by Society of Nuclear Medicine in Journal of Nuclear Medicine
- Vol. 49 (10), 1601-1605
- https://doi.org/10.2967/jnumed.108.053462
Abstract
Graft infection is a serious complication to vascular surgery. The aim of this study was to assess 18F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection. Methods: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for 18F-FDG accumulation. Clinical and biochemical data were obtained from patient records. Results: High 18F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation. Conclusion: 18F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by 18F-FDG PET/CT is evident.Keywords
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