Lead Tetraacetate Cleavage of Chiral Phenylglycinol Derived Secondary Amines Without Racemization
- 1 July 1993
- journal article
- research article
- Published by Informa UK Limited in Synthetic Communications
- Vol. 23 (14), 2055-2064
- https://doi.org/10.1080/00397919308009866
Abstract
Diastereomerically enriched N-(1,1-disubstituted methyl)(2 ‘-hydroxyl’-phenylethyl) amines were oxidatively converted to enantiomerically enriched primary disubstituted methylamines in excellent yields without racemization, using an improved lead tetraacerate (LTA) procedure.Keywords
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