The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation
- 1 September 1991
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 353 (6342), 321-325
- https://doi.org/10.1038/353321a0
Abstract
X-ray crystallography reveals electron density in the antigen-binding site of HLA-B27 that is an interpretable image of nonameric peptides in a largely extended conformation. Clear density exists for the main chain and several side chains and is consistent with the sequence of 11 nonameric self-peptides eluted from HLA-B27 (see accompanying article1). Pockets in the antigen-binding cleft bind four side chains and the amino and carboxyl termini of the peptide.This publication has 38 references indexed in Scilit:
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