Congestive Heart Failure
- 1 July 1951
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Cell Metabolism
- Vol. 4 (1), 54-69
- https://doi.org/10.1161/01.cir.4.1.54
Abstract
Metabolic studies were made on the effects of salt restriction and the administration of mercurials on the electrolyte metabolism of patients in congestive failure. Varying degrees of hyponatremia and hypochloremic alkalosis were noted. Significant disturbances in potassium balance were not observed and normal potassium values were found in biopsy specimens of skeletal muscle. The alkalosis can be attributed to the effect of mercurials on chloride excretion which is relatively greater than their effect on sodium. The continued administration of mercurials resulted in electrolyte disturbances which prevented diuresis. When these abnormalities were corrected the mercurials again became effective.Keywords
This publication has 24 references indexed in Scilit:
- THE SALT DEPLETION SYNDROME FOLLOWING MERCURIAL DIURESIS IN ELDERLY PERSONSThe American Journal of the Medical Sciences, 1950
- STUDIES ON DIURETICS. II. THE RELATIONSHIP BETWEEN GLOMERULAR FILTRATION RATE, PROXIMAL TUBULAR ABSORPTION OF SODIUM AND DIURETIC EFFICACY OF MERCURIALS 1JCI Insight, 1950
- ELECTROLYTE CHANGES IN HUMAN STRIATED MUSCLE IN ACIDOSIS AND ALKALOSISJCI Insight, 1949
- THE RELATION OF SERUM BICARBONATE CONCENTRATION TO MUSCLE COMPOSITION 1JCI Insight, 1948
- A system for the routine treatment of the failing heartAmerican Journal Of Medicine, 1947
- The retention of electrolyte during recovery fromsevere dehydration due to diarrheaThe Journal of Pediatrics, 1946
- Salyrgan and Ammonium Chloride as Diuretics in Cardiac OedemaActa Medica Scandinavica, 1934
- SERUM ELECTROLYTE STUDIES IN NORMAL AND PATHOLOGICAL CONDITIONS: PNEUMONIA, RENAL EDEMA, CARDIAC EDEMA, UREMIC AND DIABETIC ACIDOSISJCI Insight, 1930
- A STUDY OF THE ACTION OF AMMONIUM CHLORID AND ORGANIC MERCURY COMPOUNDSJCI Insight, 1926
- OBSERVATIONS ON THE USE OF NOVASUROL IN EDEMA DUE TO HEART FAILUREJCI Insight, 1925