Hormone Binding and Co-regulator Binding to the Glucocorticoid Receptor are Allosterically Coupled
Open Access
- 1 May 2010
- journal article
- Published by Elsevier BV
- Vol. 285 (20), 15256-15267
- https://doi.org/10.1074/jbc.m110.108118
Abstract
No abstract availableThis publication has 86 references indexed in Scilit:
- An epistatic ratchet constrains the direction of glucocorticoid receptor evolutionNature, 2009
- Quantification of the Vitamin D Receptor−Coregulator InteractionBiochemistry, 2009
- The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1Proceedings of the National Academy of Sciences of the United States of America, 2008
- Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNANature, 2008
- Modulators of the structural dynamics of the retinoid X receptor to reveal receptor functionProceedings of the National Academy of Sciences of the United States of America, 2007
- Crystal Structure of an Ancient Protein: Evolution by Conformational EpistasisScience, 2007
- A Conformational Switch in the Ligand-binding Domain Regulates the Dependence of the Glucocorticoid Receptor on Hsp90Journal of Molecular Biology, 2007
- Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometryProtein Science, 2006
- The Glucocorticoid Receptor: Rapid Exchange with Regulatory Sites in Living CellsScience, 2000
- The RXR heterodimers and orphan receptorsCell, 1995