Effect of defects on thermal denaturation of DNA oligomers
- 20 September 2001
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review E
- Vol. 64 (4), 042901
- https://doi.org/10.1103/physreve.64.042901
Abstract
Effect of defects on the melting profile of short heterogeneous DNA chains is calculated using the Peyrard-Bishop Hamiltonian. On-site potential on a defect site is represented by a potential that has only a short-range repulsion and a flat part without well of the Morse potential. Stacking energy between two neigbouring pairs involving a defect site is also modified. The results are found to be in good agreement with the experiments.Keywords
Other Versions
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