Critical Periods and Amblyopia
Open Access
- 1 April 1998
- journal article
- review article
- Published by American Medical Association (AMA) in American Journal of Ophthalmology
- Vol. 116 (4), 502-505
- https://doi.org/10.1001/archopht.116.4.502
Abstract
During the past 20 years, basic science has shown that there are different critical periods for different visual functions during the development of the visual system. Visual functions processed at higher anatomical levels within the system have a later critical period than functions processed at lower levels. This general principle suggests that treatments for amblyopia should be followed in a logical sequence, with treatment for each visual function to be started before its critical period is over. However, critical periods for some visual functions, such as stereopsis, are not yet fully determined, and the optimal treatment is, therefore, unknown. This article summarizes the current extent of our knowledge and points to the gaps that need to be filled.Keywords
This publication has 24 references indexed in Scilit:
- Development of orientation selectivity in ferret visual cortex and effects of deprivationJournal of Neuroscience, 1993
- Critical period for monocular deprivation in the cat visual cortexJournal of Neurophysiology, 1992
- The effect of dark rearing on the time course of the critical period in cat visual cortexDevelopmental Brain Research, 1991
- Identifying Amblyopia Using Associated Conditions, Acuity, and Nonacuity FeaturesOptometry and Vision Science, 1985
- The development of ocular dominance columns in normal and visually deprived monkeysJournal of Comparative Neurology, 1980
- Prolonged sensitivity to monocular deprivation in dark-reared catsJournal of Neurophysiology, 1980
- On the nature of the neural abnormality in human amblyopia; neural aberrations and neural sensitivity lossPflügers Archiv - European Journal of Physiology, 1978
- Kittens reared in a unidirectional environment: evidence for a critical period.The Journal of Physiology, 1976
- SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYEJournal of Neurophysiology, 1963
- A Study of Separation Difficulty*American Journal of Ophthalmology, 1962