Helicobacter pylori Infection Is Associated With Low Serum Ferritin Levels in Israeli Arab Children—A Seroepidemiologic Study
- 1 August 2009
- journal article
- Published by Wiley in Journal of Pediatric Gastroenterology and Nutrition
- Vol. 49 (2), 262-264
- https://doi.org/10.1097/mpg.0b013e31818f0a0d
Abstract
We examined the association between Helicobacter pylori seropositivity and low ferritin levels in sera of 509 Israeli Arab children aged 1 to 19 years. Serum ferritin levels were measured using the immunoturbidity assay. ELISA was used to detect serum IgG antibodies to H pylori and IgG antibodies to H pylori CagA strains. Low ferritin level was found between 14.5% and 8.6% of the H pylori seropositive and seronegative participants, respectively (P = 0.035). A trend for a higher frequency of low ferritin was detected among H pylori-CagA seropositive children. Multivariate analysis showed an increased frequency of low ferritin only among children younger than or equal to 5 years: adjusted OR 4.62 (95% CI 1.53-13.99) P = 0.007.Keywords
This publication has 16 references indexed in Scilit:
- The Incidence of Anemia in an Israeli Population: A Population Analysis for Anemia in 34512 Israeli Infants Aged 9 to 18 MonthsPEDIATRICS, 2006
- Prevalence and risk factors of Helicobacter pylori infection among healthy 3- to 5-year-old Israeli Arab childrenEpidemiology and Infection, 2006
- Endemic Iron Deficiency Associated With Helicobacter pylori Infection Among School-Aged Children in AlaskaPEDIATRICS, 2006
- Is There a Relationship Between Childhood Helicobacter Pylori Infection and Iron Deficiency Anemia?Journal of Tropical Pediatrics, 2005
- Does Helicobacter pylori infection relate to iron deficiency anaemia in prepubescent children under 12 years of age?Acta Paediatrica, 2003
- Evaluation of Two Commercial Enzyme Immunoassays, Testing Immunoglobulin G (IgG) and IgA Responses, for Diagnosis of Helicobacter pylori Infection in ChildrenJournal of Clinical Microbiology, 2001
- Helicobacter pylori–associated iron-deficiency anemia in adolescent female athletesThe Journal of Pediatrics, 2001
- Helicobacter Pylori Infection and Serum Ferritin: A Population-Based Study Among 1806 Adults in GermanyThe American Journal of Gastroenterology, 2001
- Randomized Placebo‐Controlled Trial of Helicobacter pylori Eradication for Iron‐Deficiency Anemia in Preadolescent Children and AdolescentsHelicobacter, 1999
- Prevalence of Iron Deficiency in the United StatesJAMA, 1997