Radical Azidonation of Aldehydes
- 1 November 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 68 (24), 9453-9455
- https://doi.org/10.1021/jo035163v
Abstract
Aliphatic and aromatic aldehydes can be converted to acyl azides by treatment with iodine azide at 0−25 °C. If the reaction is performed at reflux Curtius rearrangement occurs and carbamoyl azides are obtained in 70−97% yield from the aldehyde. The reaction was shown to have a radical mechanism.Keywords
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- Carbamoyl AzidesChemical Reviews, 1965