Squamous Cell Carcinoma of the Gingiva: Histological Classification and Grading of Malignancy
- 1 January 1975
- journal article
- research article
- Published by Informa UK Limited in Acta Oto-Laryngologica
- Vol. 79 (1-2), 146-154
- https://doi.org/10.3109/00016487509124667
Abstract
A histological classification and grading of malignancy has been performed on the initial biopsies from 124 patients with squamous-cell carcinoma of the gingiva treated during the period 1958-69 at the Karolinska hospital. Six different morphological parameters were evaluated with respect to the tumour cell population and the tumour-host relationship estimated in terms of a four-point scale. This permitted grading with total points ranging from 6-24. A strong correlation was found between the degree of histological malignancy and the fatal outcome of the disease. Thus a tumour with a point value of 16 almost always led to the death of the patient while the best results were achieved with surgery alone in the group of small cancers (T1 + T2) with low total malignancy points.Keywords
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