Keratin 17 Expression Correlates with Tumor Progression and Poor Prognosis in Gastric Adenocarcinoma
- 14 June 2012
- journal article
- Published by Springer Science and Business Media LLC in Annals of Surgical Oncology
- Vol. 19 (11), 3506-3514
- https://doi.org/10.1245/s10434-012-2437-9
Abstract
Keratin 17 (K17) is regarded as a basal/myoepithelial cell keratin and is known to be inducible in activated keratinocytes. The high frequency of K17 expression in pancreaticobiliary nonmucinous adenocarcinoma or basal-like breast carcinoma has previously been described. However, its expression in gastric cancer (GC) is controversial.Keywords
This publication has 40 references indexed in Scilit:
- Keratins in health and cancer: more than mere epithelial cell markersOncogene, 2010
- Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skinNature Genetics, 2010
- Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008International Journal of Cancer, 2010
- Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patientsEuropean Journal of Surgical Oncology, 2009
- Cytokeratin-19 mRNA-Positive Circulating Tumor Cells After Adjuvant Chemotherapy in Patients With Early Breast CancerJournal of Clinical Oncology, 2009
- The human keratins: biology and pathologyHistochemistry and Cell Biology, 2008
- Prognostic impact of PCR-based identification of isolated tumour cells in the peritoneal lavage fluid of gastric cancer patients who underwent a curative R0 resectionBritish Journal of Cancer, 2007
- Differences in the histological findings, phenotypic marker expressions and genetic alterations between adenocarcinoma of the gastric cardia and distal stomachBritish Journal of Cancer, 2007
- Distribution and significance of 14‐3‐3σ, a novel myoepithelial marker, in normal, benign, and malignant breast tissueThe Journal of Pathology, 2004
- Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsProceedings of the National Academy of Sciences of the United States of America, 2001