Amlodipine‐induced gingival overgrowth
- 1 April 1994
- journal article
- Published by Wiley in Journal of Clinical Periodontology
- Vol. 21 (4), 281-283
- https://doi.org/10.1111/j.1600-051x.1994.tb00318.x
Abstract
Amlodipine is a calcium channel blocker used in the management of angina and hypertension. We report 3 cases of gingival overgrowth in adult dentate patients associated with chronic usage of this drug. Gingival changes occurred within 3 months of dosage and appeared to be compounded by the patient's existing periodontal condition. In all 3 patients, there was sequestration of amlodipine in their crevicular fluid. The significance of this finding in relation to the pathogenesis of this unwanted effect remains to be elucidated.Keywords
This publication has 15 references indexed in Scilit:
- Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowthThe Lancet, 1992
- The incidence and severity of nifedipine‐induced gingival overgrowthJournal of Clinical Periodontology, 1992
- Nifedipine‐induced gingival overgrowthJournal of Clinical Periodontology, 1992
- Calcium channel blockers and gingival overgrowthBritish Dental Journal, 1991
- Felodipine-induced gingival hyperplasia: a clinical and histologic studyJournal of Oral Pathology & Medicine, 1991
- The pharmacokinetic profile of amlodipineAmerican Heart Journal, 1989
- Nitrendipine–Induced Gingival Overgrowth in DogsThe Journal of Periodontology, 1989
- Gingival Hyperplasia in Dogs Induced by Oxodipine, a Calcium Channel Blocking AgentToxicologic Pathology, 1988
- The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patientsJournal of Clinical Periodontology, 1985