Animal Experiments in Biomedical Research: A Historical Perspective
Open Access
- 18 March 2013
- Vol. 3 (1), 238-273
- https://doi.org/10.3390/ani3010238
Abstract
The use of non-human animals in biomedical research has given important contributions to the medical progress achieved in our day, but it has also been a cause of heated public, scientific and philosophical discussion for hundreds of years. This review, with a mainly European outlook, addresses the history of animal use in biomedical research, some of its main protagonists and antagonists, and its effect on society from Antiquity to the present day, while providing a historical context with which to understand how we have arrived at the current paradigm regarding the ethical treatment of animals in research.Keywords
This publication has 105 references indexed in Scilit:
- Descartes: The Smear and Related MisconstrualsJournal for the Theory of Social Behaviour, 2011
- Can Animal Models of Disease Reliably Inform Human Studies?PLoS Medicine, 2010
- Louis Pasteur's discovery of molecular chirality and spontaneous resolution in 1848, together with a complete review of his crystallographic and chemical workActa Crystallographica Section A Foundations of Crystallography, 2009
- The Contributions of Paul Ehrlich to Pharmacology: A Tribute on the Occasion of the Centenary of His Nobel PrizePharmacology, 2008
- Animal research: a moral scienceEMBO Reports, 2007
- The ethics of animal researchEMBO Reports, 2007
- Computational modeling of physiological systemsPhysiological Genomics, 2005
- Broken Limits to Life ExpectancyScience, 2002
- Descartes on the Moral Status of AnimalsArchiv für Geschichte der Philosophie, 1998
- Drawing the life-blood of physiology: Vivisection and the Physiologists' dilemma, 1870–1900Annals of Science, 1986