Semiconductor Quantum Dots in Chemical Sensors and Biosensors
Open Access
- 10 September 2009
- Vol. 9 (9), 7266-7286
- https://doi.org/10.3390/s90907266
Abstract
Quantum dots are nanometre-scale semiconductor crystals with unique optical properties that are advantageous for the development of novel chemical sensors and biosensors. The surface chemistry of luminescent quantum dots has encouraged the development of multiple probes based on linked recognition molecules such as peptides, nucleic acids or small-molecule ligands. This review overviews the design of sensitive and selective nanoprobes, ranging from the type of target molecules to the optical transduction scheme. Representative examples of quantum dot-based optical sensors from this fast-moving field have been selected and are discussed towards the most promising directions for future research.Keywords
This publication has 93 references indexed in Scilit:
- Sensing Caspase 3 Activity with Quantum Dot−Fluorescent Protein AssembliesJournal of the American Chemical Society, 2009
- Quantum Dots — Characterization, Preparation and Usage in Biological SystemsInternational Journal of Molecular Sciences, 2009
- Multiplex Detection of Protease Activity with Quantum Dot Nanosensors Prepared by Intein-Mediated Specific BioconjugationAnalytical Chemistry, 2008
- Bioconjugated quantum dots for in vivo molecular and cellular imagingAdvanced Drug Delivery Reviews, 2008
- A Reactive Peptidic Linker for Self-Assembling Hybrid Quantum Dot−DNA BioconjugatesNano Letters, 2007
- pH-Sensitive Photoluminescence of CdSe/ZnSe/ZnS Quantum Dots in Human Ovarian Cancer CellsThe Journal of Physical Chemistry C, 2007
- A mechanism to signal receptor–substrate interactions with luminescent quantum dotsProceedings of the National Academy of Sciences of the United States of America, 2006
- Quantum-Dot-Based Nanosensor for RRE IIB RNA−Rev Peptide Interaction AssayJournal of the American Chemical Society, 2006
- Protease-activated quantum dot probesBiochemical and Biophysical Research Communications, 2005
- The effect of tetraalkylammonium and alkyl sulfate salts on the fluorescence bands of quantum-sized CdSJournal of Photochemistry and Photobiology A: Chemistry, 1998