Gastrointestinal stromal tumors and leiomyosarcomas
- 19 February 2008
- journal article
- review article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 97 (4), 350-359
- https://doi.org/10.1002/jso.20970
Abstract
Only recently has gastrointestinal stromal tumor (GIST) been recognized as the most frequent GI mesenchymal neoplasm. Prior to the use of KIT staining, most GI stromal tumors were identified as leiomyosarcoma (LMS). For primary GIST, surgery remains the principal treatment and adjuvant imatinib may improve outcomes. Multimodality therapy may also be effective in patients with metastatic GIST. In this review, we summarize the epidemiology, clinicopathologic features, natural history, and clinical management of LMS and GIST. J. Surg. Oncol. 2008;97:350–359.This publication has 86 references indexed in Scilit:
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