Pulmonary Capillary Hemangiomatosis–Like Foci
Open Access
- 1 May 2000
- journal article
- case report
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 113 (5), 655-662
- https://doi.org/10.1309/9r7n-19bp-p5qj-u8e7
Abstract
Pulmonary capillary hemangiomatosis (PCH) typically occurs in young patients who have signs and symptoms of pulmonary hypertension. It commonly is misdiagnosed in life as pulmonary veno-occlusive disease, and the correct diagnosis usually is not made until autopsy. Autopsy records, including reports, gross photographs, histologic slides, clinical histories, and radiographic images, were reviewed to identify cases with morphologic changes characteristic of PCH. The previous case reports describe PCH as a diffuse process throughout both lung fields. All patients were symptomatic, and most died of the disease. This article details 8 cases of PCH-like foci that were incidental findings at autopsy in which the patients did not have symptoms of pulmonary hypertension nor did PCH contribute in any way to death. This is the first case series that describes pathologic changes of PCH occurring in this setting, and we hope to provide more interest in PCH and its natural history.Keywords
This publication has 20 references indexed in Scilit:
- Case of the MonthArchives of Internal Medicine, 1999
- Pulmonary Capillary Hemangiomatosis as a Rare Cause of Pulmonary HypertensionPathology - Research and Practice, 1996
- Pulmonary capillary hemangiomatosis: A clinicopathologic reviewThe Annals of Thoracic Surgery, 1994
- Pulmonary Capillary Hemangiomatosis: Report of a Case and Review of the LiteratureRespiration, 1992
- Histopathology of primary pulmonary hypertension. A qualitative and quantitative study of pulmonary blood vessels from 58 patients in the National Heart, Lung, and Blood Institute, Primary Pulmonary Hypertension Registry.Circulation, 1989
- Pulmonary Capillary Hemangiomatosis: A Report of Three Cases and a Review of the LiteratureAmerican Review of Respiratory Disease, 1989
- Treatment of Pulmonary Hemangiomatosis with Recombinant Interferon Alfa-2aNew England Journal of Medicine, 1989
- Thoracic Hemangiomatosis Masquerading as Interstitial Lung DiseaseChest, 1988
- Pulmonary capillary hemangiomatosisHuman Pathology, 1986
- Capillary haemangiomatosis of the lungsHistopathology, 1978