Changing Epidemiology of Human Brucellosis, China, 1955–2014
Top Cited Papers
Open Access
- 1 February 2017
- journal article
- research article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 23 (2), 184-194
- https://doi.org/10.3201/eid2302.151710
Abstract
Brucellosis, a zoonotic disease, was made statutorily notifiable in China in 1955. We analyzed the incidence and spatial–temporal distribution of human brucellosis during 1955–2014 in China using notifiable surveillance data: aggregated data for 1955–2003 and individual case data for 2004–2014. A total of 513,034 brucellosis cases were recorded, of which 99.3% were reported in northern China during 1955–2014, and 69.1% (258, 462/374, 141) occurred during February–July in 1990–2014. Incidence remained high during 1955–1978 (interquartile range 0.42–1.0 cases/100,000 residents), then decreased dramatically in 1979–1994. However, brucellosis has reemerged since 1995 (interquartile range 0.11–0.23 in 1995–2003 and 1.48–2.89 in 2004–2014); the historical high occurred in 2014, and the affected area expanded from northern pastureland provinces to the adjacent grassland and agricultural areas, then to southern coastal and southwestern areas. Control strategies in China should be adjusted to account for these changes by adopting a One Health approach.Keywords
This publication has 30 references indexed in Scilit:
- Epidemiological features and risk factors associated with the spatial and temporal distribution of human brucellosis in ChinaBMC Infectious Diseases, 2013
- Changes of predominant species/biovars and sequence types of Brucellaisolates, Inner Mongolia, ChinaBMC Infectious Diseases, 2013
- Brucellosis in low-income and middle-income countriesCurrent Opinion in Infectious Diseases, 2013
- Brucellosis in Guangdong Province, People’s Republic of China, 2005–2010Emerging Infectious Diseases, 2013
- Molecular Epidemiology and Antibiotic Susceptibility of Livestock Brucella melitensis Isolates from Naryn Oblast, KyrgyzstanPLoS Neglected Tropical Diseases, 2013
- Clinical Manifestations of Human Brucellosis: A Systematic Review and Meta-AnalysisPLoS Neglected Tropical Diseases, 2012
- Global Burden of Human Brucellosis: A Systematic Review of Disease FrequencyPLoS Neglected Tropical Diseases, 2012
- Representative Seroprevalences of Brucellosis in Humans and Livestock in KyrgyzstanEcohealth, 2011
- Human brucellosisThe Lancet Infectious Diseases, 2007
- BrucellosisThe New England Journal of Medicine, 2005