Chemical Etiology of Nucleic Acid Structure
- 25 June 1999
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 284 (5423), 2118-2124
- https://doi.org/10.1126/science.284.5423.2118
Abstract
Systematic chemical studies indicate that the capability of Watson-Crick base-pairing is widespread among potentially natural nucleic acid alternatives taken from RNA's close structural neighborhood. A comparison of RNA and such alternatives with regard to chemical properties that are fundamental to the biological function of RNA provides chemical facts that may contain clues to RNA's origin.Keywords
This publication has 69 references indexed in Scilit:
- Formation of Oligonucleotide−PNA−Chimeras by Template-Directed LigationJournal of the American Chemical Society, 1998
- 2‘-Deoxy-3-isoadenosine Forms Hoogsteen-Type Base Pairs with Thymidine in the d(CG[iA]TCG)2 Duplex1Journal of the American Chemical Society, 1996
- Enzymic recognition of the base pair between isocytidine and isoguanosineBiochemistry, 1993
- Oligodeoxynucleotides that contain 2',5'' linkages: synthesis and hybridization propertiesJournal of the American Chemical Society, 1992
- Nonenzymic template-directed synthesis on oligodeoxycytidylate sequences in hairpin oligonucleotidesJournal of the American Chemical Society, 1992
- Rna catalysis and the origin of lifeOrigins of life and evolution of the biosphere, 1985
- Early Chemical Evolution of Nucleic Acids: A Theoretical ModelScience, 1977
- Self‐Organization of Molecular Systems and Evolution of the Genetic ApparatusAngewandte Chemie-International Edition, 1972
- Evolution of the genetic apparatusJournal of Molecular Biology, 1968
- An Unusual Photochemical Rearrangement in the Synthesis of Adenine from Hydrogen Cyanide1Journal of the American Chemical Society, 1966