IgA nephropathy in association with Crohn's disease: a case report and brief review of the literature
Open Access
- 6 May 2010
- journal article
- case report
- Published by Taylor & Francis Ltd in Renal Failure
- Vol. 32 (4), 523-527
- https://doi.org/10.3109/08860221003710554
Abstract
A case of immunoglobulin A nephropathy (IgAN) complicating a 10-year history of biopsy-proven Crohn's disease in a 31-year-old man is described. The patient presented with mild proteinuria and impaired renal function in the setting of an exacerbation of Crohn's disease. Renal biopsy showed IgAN. The patient responded to steroid treatment with clinical remission of the bowel disease and improvement of renal function, while proteinuria remained unchanged. IgA glomerulonephritis is rarely associated with Crohn's disease with only a few previously described cases. We briefly review these cases together with an overview of potential pathophysiological connections between these two diseases.Keywords
This publication has 20 references indexed in Scilit:
- Tubulointerstitial nephritis as an extraintestinal manifestation of Crohn's diseaseNature Clinical Practice Nephrology, 2008
- Secondary IgA NephropathySeminars in Nephrology, 2008
- A Comparison of GFR estimating formulae based upon s-cystatin C and s-creatinine and a combination of the twoNephrology Dialysis Transplantation, 2007
- 5-Aminosalicylates and renal function in inflammatory bowel diseaseInflammatory Bowel Diseases, 2007
- Urogenital Complications of Crohn's DiseaseThe American Journal of Gastroenterology, 2006
- Extraintestinal manifestations and complications in inflammatory bowel diseasesWorld Journal of Gastroenterology, 2006
- IgA antiglomerular basement membrane nephritis associated with crohn's disease: a case report and review of glomerulonephritis in inflammatory bowel diseaseAmerican Journal of Kidney Diseases, 2003
- Renal and Urologic Complications of Inflammatory Bowel DiseaseThe American Journal of Gastroenterology, 1998
- Case Report: Sclerosing Cholangitis, Inflammatory Bowel Disease, and Glomerulonephritis (A Case Report of a Rare Triad)Digestive Diseases and Sciences, 1997
- Immune-Complex Glomerulonephritis in Crohnʼs DiseaseJournal of Pediatric Gastroenterology and Nutrition, 1986