Hydrogen Peroxide-Mediated Killing of Caenorhabditis elegans : a Common Feature of Different Streptococcal Species
Open Access
- 1 February 2004
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 72 (2), 1192-1194
- https://doi.org/10.1128/iai.72.2.1192-1194.2004
Abstract
Recently, we reported that Streptococcus pyogenes kills Caenorhabditis elegans by the use of hydrogen peroxide (H 2 O 2 ). Here we show that diverse streptococcal species cause death of C. elegans larvae in proportion to the level of H 2 O 2 produced. H 2 O 2 may mask the effects of other pathogenicity factors of catalase-negative bacteria in the C. elegans infection model.Keywords
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