Drug‐Induced Neutropenias in the Stockholm Region 1976–1977

Abstract

Previously the incidence and causes of drug-induced neutropenia in the Stockholm region during 1973-1975 was reviewed. An equivalent study for 1976-1977 is presented. The yearly incidence of drug-induced neutropenia, cytostatics excluded, remained around 0.01.permill.. About 50% of the cases were caused by sulfonamides. Among the other causes, antithyroid drugs and phenothiazines were most frequent. The mortality rate was 27%, in contrast to only 2% in the previous study. Of the 7 patients who died, 5 had taken sulfonamides.