The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: The California Lupus Surveillance Project
Top Cited Papers
- 10 September 2017
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatology
- Vol. 69 (10), 1996-2005
- https://doi.org/10.1002/art.40191
Abstract
Estimates of the incidence and prevalence of systemic lupus erythematosus (SLE) in the US have varied widely. The purpose of this study was to conduct the California Lupus Surveillance Project (CLSP) to determine credible estimates of SLE incidence and prevalence, with a special focus on Hispanics and Asians. The CLSP, which is funded by the Centers for Disease Control and Prevention, is a population-based registry of individuals with SLE residing in San Francisco County, CA, from January 1, 2007 through December 31, 2009. Data sources included hospitals, rheumatologists, nephrologists, commercial laboratories, and a state hospital discharge database. We abstracted medical records to ascertain SLE cases, which we defined as patients who met ≥4 of the 11 American College of Rheumatology classification criteria for SLE. We estimated crude and age-standardized incidence and prevalence, which were stratified by sex and race/ethnicity. The overall age-standardized annual incidence rate was 4.6 per 100,000 person-years. The average annual period prevalence was 84.8 per 100,000 persons. The age-standardized incidence rate in women and men was 8.6 and 0.7 per 100,000 person-years, respectively. This rate was highest among black women (30.5), followed by Hispanic women (8.9), Asian women (7.2), and white women (5.3). The age-standardized prevalence in women per 100,000 persons was 458.1 in blacks, 177.9 in Hispanics, 149.7 in Asians, and 109.8 in whites. Capture–recapture modeling estimated 33 additional incident cases and 147 additional prevalent cases. Comprehensive methods that include intensive case-finding provide more credible estimates of SLE in Hispanics and Asians, and confirm racial and ethnic disparities in SLE. The disease burden of SLE is highest in black women, followed by Hispanic women, Asian women, and white women.Keywords
Funding Information
- Centers for Disease Control and Prevention
- National Center for Chronic Disease Prevention and Health Promotion (A114297)
This publication has 15 references indexed in Scilit:
- Association of Asian ethnicity with disease activity in SLE: an observational study from the Monash Lupus ClinicLupus, 2013
- Lupus in Hispanics: A matter of serious concernCleveland Clinic Journal of Medicine, 2012
- Systemic Lupus ErythematosusThe New England Journal of Medicine, 2011
- Recent insights in the epidemiology of autoimmune diseases: Improved prevalence estimates and understanding of clustering of diseasesJournal of Autoimmunity, 2009
- Population‐based lupus registries: Advancing our epidemiologic understandingArthritis Care & Research, 2009
- A multiethnic, multicenter cohort of patients with systemic lupus erythematosus (SLE) as a model for the study of ethnic disparities in SLEArthritis Care & Research, 2007
- Systemic lupus erythematosus in three ethnic groups: III A comparison of characteristics early in the natural history of the LUMINA cohortLupus, 1999
- Updating the American college of rheumatology revised criteria for the classification of systemic lupus erythematosusArthritis & Rheumatism, 1997
- Incidence of systemic lupus erythematosus race and gender differencesArthritis & Rheumatism, 1995
- The 1982 revised criteria for the classification of systemic lupus erythematosusArthritis & Rheumatism, 1982