Rhabdomyolysis following Severe Physical Exercise in a Patient with Predisposition to Malignant Hyperthermia
Open Access
- 1 June 1998
- journal article
- case report
- Published by SAGE Publications in Anaesthesia and Intensive Care
- Vol. 26 (3), 315-318
- https://doi.org/10.1177/0310057x9802600317
Abstract
A 21-year-old man suffered from exertional heat stroke with impaired consciousness and rhabdomyolysis after strenuous physical exercise. Within two weeks the patient recovered completely without any specific therapy. Based on the symptoms and laboratory investigations, this episode suggested a moderate form of malignant hyperthermia. An in vitro contracture test was performed and a predisposition to malignant hyperthermia was diagnosed; other muscular diseases were excluded by histological examination. At present, the in vitro contracture test is the only method used to determine susceptibility to malignant hyperthermia and should be performed when the diagnosis is suggested on clinical grounds.Keywords
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